TISSUE INVASION AND METASTASIS	ANGPTL3	CXCR4	LAMA4	EFNB1	MAP3K8	RHOA	TBL1XR1	WNT5B	LAMA5	ITGA2B	SDC1	NGF	NFKB2	NTNG1	HCK	PDPK1	CDH5	WNT10A	MAPKAPK2	PIP5K1C	CDC42BPA	MYL2	ABL2	RAB11A	TGFA	ARRB1	ITGA5	PLCG1	RASA1	RRAS	ENG	CLDN15	PIK3CD	LAMB2	CNR1	WAS	CLDN20	FPR2	PARD3	SDC3	ELMO2	GP1BA	FYN	LIMK1	PXN	MAP3K2	XIAP	ERBB3	CD6	NRXN2	PRKACB	GFRA1	TNF	PRKACA	S1PR1	ACTN3	ITGB1	PLXND1	DUSP1	BAMBI	COL6A3	NPHS1	NTF3	EPHA8	MMP7	CDC42	RAPGEF1	PTEN	FGF10	CD34	FLNA	ALCAM	CRKL	LAMC1	AKT1	IRS2	SMAD2	CAV1	MADCAM1	BMP7	ACTR2	CD44	CLDN3	TLR2	ID1	GNG2	LAMB1	TNR	CLDN25	GNA12	ITGAL	EFNA3	NCKAP1	SPHK1	WNT9A	SSX2IP	DPP4	NLGN2	CTNNA1	PRKCD	PLCB3	EPHB2	CASP8	TRIP6	FGFR1	EFNA1	GNB5	MYH9	EPHB1	ITGB2	CBL	CNTNAP1	FAT1	IL12B	NRXN1	ARHGEF7	CD99	NTRK2	JUP	NCAM1	CDH4	F11R	RB1	COL1A1	EPHA2	FN1	CLDN22	IGF1R	MYLPF	PARVA	EPHA3	PIK3CB	SNAI1	WNT7A	WNT3A	NFASC	SELPLG	DDX5	ITGAM	GNAO1	TJP1	PARVG	EPHA4	ACTN1	MYC	CXCR3	MAPK7	ACVR1	ARF6	RAB5A	ICAM3	CD22	EXOC2	CLDN1	ACVR2B	CLDN10	RPS6KB1	CLDN19	NTRK1	PIK3CA	CD36	MAPK8IP3	LPAR1	SIGLEC1	GPC4	LAMB3	GAB1	NCK2	MAP4K1	WNT2	WASF2	CD86	CADM3	FER	MAPK14	PTK2	CTTN	STAT5B	DVL1	CADM1	TLR4	MTOR	ARF4	F2RL3	CXCL12	ARHGDIA	WASL	CLDN9	PLCB1	NRCAM	PLD2	WNT8A	LCP2	DOCK2	PRKCE	KDR	PDGFB	MMP2	COMP	NCAN	MSN	FZD2	PRKCG	SYMPK	RAF1	JUN	KIT	EGFR	VAV2	SMPD1	MAP3K7	JAM2	APC	CASP3	ARRB2	NRG2	ERBB2	ACTN4	FGF1	CD63	SOS1	GNB1	PRKCQ	GPC3	HGF	MAP3K3	CD47	MAP2K6	NLGN3	CLDN16	IBSP	CD28	SHC2	NFATC2	PAK2	PVRL2	EPHA1	ITGB7	CTNNA3	FLT1	TLN1	ARHGEF1	LAMB4	MAP4K3	PPP3R1	RALA	ERBB4	MAPRE1	TAOK2	MAPKAPK5	SMAD3	MMP3	NEO1	SIPA1	ITGAE	BDNF	CLDN18	RAP1B	PRKG1	ITGB5	GNAI3	PFN1	LPAR3	SRC	CASK	PTPRJ	WNT5A	WNT9B	ZAP70	CD2AP	IKBKB	PAK1	CLDN23	NTRK3	DRD2	PARD6A	MAPK12	PKN2	ACKR3	ITGA7	RAC2	PPARD	ELMO1	ITGA8	FGFR4	THBS1	KITLG	BRAF	RND2	PTPRF	THBS2	VAV3	ITGA4	CLDN17	RASGRF1	EZR	LAMA2	FGFR2	TNXB	EFNB2	PTK6	CDH2	EGF	NRG1	ACVRL1	RND3	VASP	ESR1	PLEKHA7	PRICKLE1	RAC1	NF1	EPHB4	GRB2	BAIAP2	RRAS2	WNT11	WASF1	IL1A	EREG	ARHGAP35	PRKCZ	FLT4	RALGDS	PTPN6	COL6A6	P2RY1	HPSE	MYH2	LPAR2	MYL9	PTPRM	YES1	SHROOM2	NGFR	ETS1	ACTB	PTPN1	PECAM1	NCK1	GP9	ARPC5	ARAP3	MDK	THBS3	ITGA3	PTPN11	CLDN8	PTK2B	MAP2K2	VTN	NODAL	ITGA9	CLDN4	PIP5K1A	GPC2	TGFBR2	MAPKAPK3	BCL2L1	EPHB3	ABI2	MAX	APC2	CLDN11	PRKCA	SELL	CCND1	SDC4	WASF3	FAT4	TNC	BMPR2	MAP2K4	PDGFA	MAP3K12	RHOC	BCL2	PIK3R1	WNT16	SPN	BMPR1A	CDKN1A	TLN2	LAMC3	ABL1	PTPRC	THY1	EXOC3	VCAN	SHC3	PVR	GNAI1	TGFB1	ITGA6	CASP9	PRKD2	CFL1	ITGB4	AKT2	ITGA1	PDGFRA	NFKB1	MAP2K3	PRKCH	HSPB1	RET	CRK	IL2	GP5	CDK1	MAPK3	DOCK1	PDGFRB	ESAM	DVL3	PRKCI	LAMA3	VAV1	TNFRSF1A	GRIN2A	FAS	IGF1	MMP14	ROCK2	COL6A1	ACVR2A	VWF	JAM3	WNT1	PLCB2	PLAU	TRAF6	DAAM1	WNT4	L1CAM	SMAD4	LAT	ITGAV	FES	CDH1	CD2	DICER1	SPP1	LAMC2	ZYX	CLDN6	CLDN2	CCL11	BMP2	MMP9	MAPK8IP2	IQGAP1	PSEN1	HRAS	PLAUR	UNC5C	NLGN4X	ANGPT2	TIAM1	WNT3	WNT7B	LEF1	SNAI2	NTNG2	KSR1	MAGI1	MAP4K4	FARP2	MAG	JUND	ITGA2	TGFB2	STAT3	CREBBP	NEGR1	DRD1	F2R	PPP2R2A	CDKN1B	MYLK	HLA-DRB1	CDK5	NOG	ITGB8	HIF1A	RAP1A	LAMA1	CLDN24	CAMK2G	GNAI2	OMG	TGFBR1	RDX	CAPN2	GSK3B	CTNNA2	CD4	WNT2B	FGF2	TCF7L2	NOS3	ILK	MAP3K4	CNTNAP2	CLDN14	NRAS	SELP	GJA1	VEGFA	RELN	MAP3K14	PPP3CA	CDH11	CD226	KRAS	GNAS	WNT10B	ROCK1	PARVB	EFNA5	AJUBA	FPR1	EFNA2	NRXN3	FAP	RHOB	MYH10	MAPK1	MAPK8	FIGF	FGB	HLA-DRA	WNT8B	GPC1	CDH15	PLD1	DAB1	CNTN2	CTNND1	MET	TP53	LIMA1	ITGA11	SDC2	NLGN1	ANGPT1	FRS2	RIN1	DNM2	PIK3CG	MAP3K11	MAPK13	DVL2	SELE	CLDN7	ENAH	DAXX	SHC1	NCAM2	THBS4	VCAM1	MAPK10	BSG	ACTR3	COL4A6	ITGB3	PAK4	AKT3	MAPK9	DDR2	PTPN13	DIAPH1	PPP2R1A	PTPRB	RALB	PAFAH1B1	BRK1	MAP2K1	ACTN2	ICAM2	CSF1	MAP4K2	COL1A2	PPP2CA	MAP3K1	BMX	CTNNB1	TEK	ABI1	MAP2K7	ARHGAP5	GAB2	FASLG	BIRC3	EXOC4	GP1BB	BCAR1	ITGA10	ITGB6	COL4A3	CD80	VCL	MFGE8	CSF3R	TRAF2	SLC9A1	MAPK11	PRKCB	GNA11	ICAM1	CLDN5	CBLB	TGFB3	WNT6	NOTCH2	MAP3K5	COL6A2	MAP2K5	CNTN1	INS	CDH3	HBEGF	CYFIP2	GNAQ																															
REPROGRAMMING ENERGY METABOLISM	IDH3G	COX6C	PFKFB1	TPI1	PYGL	CDKN1B	PGM2	ACLY	GAPDH	G6PC	GCK	PHGDH	PGLS	PGK1	HIF1A	MTOR	PPARG	IDH2	PDK1	NDUFS7	OGDHL	PDHA1	NDUFV2	PRPS1L1	LDHB	NDUFS1	PRKAG3	RPTOR	PRKAA2	PDHB	SDHB	MDH1	GAPDHS	VHL	SDHD	PCK2	NDUFV1	EGFR	BNIP3	ACO1	IDH1	UQCRFS1	PRKAG1	ENO3	GPI	KRAS	PYGM	SUCLG1	PFKP	ERBB2	NFE2L2	NDUFS2	TALDO1	GALM	PRPS2	CCND1	FBP1	RPE	LDHC	MAPK1	GYS2	NDUFS8	H6PD	NDUFS3	PGAM2	CYC1	COX5B	G6PC3	PHKA1	PGAM4	DLAT	TKT	PTEN	OGDH	CS	HKDC1	DLD	UQCRC2	TP53	SIRT3	UQCRQ	COX7B	FH	NOTCH1	IDH3B	SDHA	AKT1	ENO1	PFKM	HK3	AKT2	ENO2	PRKAG2	SUCLA2	PGAM1	MDH2	HK2	EDN1	COX6A2	ACACA	G6PD	BPGM	PHKG2	MAP2K1	CCNA2	PGM1	SIRT6	PCK1	SUCLG2	COX6A1	UQCRC1	FBP2	PRKAB2	PFKFB2	SLC2A4	COX7A2	GADD45B	PRKAA1	PFKL	TIGAR	PC	COX4I1	COX7A2L	PRKAB1	ALDOC	UQCR11	RPIA	IDH3A	FASN	ALDOA	BRAF	SDHC	PGK2	GYS1	SIRT1	PHKB	MDM2	COX6B1	PFKFB3	DLST	ADPGK	DNMT3A	HK1	PHKG1	MYC	PKLR	UQCRH	COX5A	PRPS1	SLC16A3	ACO2	CD36	ALDOB	COX8A	LDHA																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																				
REPLICATIVE IMMORTALITY	TERF2IP	TERF2	TERF1	CDKN1B	MIF	E2F3	ETS1	MAPK14	RAD50	TNKS	RAP1A	PPARG	ATM	WIF1	TERT	PIK3CD	MAP2K2	FGF2	NRAS	KDR	RAF1	JUN	BMI1	ACD	KRAS	PRKCA	TNF	SP1	CCND1	MAPK1	E2F1	MAPK8	PIK3R1	ID2	PPP2R1B	CDKN1A	SLX4	PTEN	TINF2	CDK4	E2F5	TP53	POT1	KLF4	TGFB1	AKT1	ETS2	SMAD2	PIK3CG	CDK2	POU5F1	AKT2	SMAD3	E2F4	TWIST1	MAPK10	FST	CDKN2A	MAPK9	AKT3	MAPK3	PPP2R1A	RTEL1	MAP2K1	FGFR1	SIRT6	FAS	IGF1	CDK6	CTNNB1	ATRX	NBN	TBX3	PPARD	PIK3R3	RB1	MSH2	IGF1R	AXIN1	PIK3R2	PIK3CB	MDM2	BMP2	CCNE1	CCND2	MAPK11	MYC	EGF	PRKCB	HRAS	CDKN2B	GRB2	CDKN2D	PIK3CA																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																	
GENOME INSTABILITY	POLE2	CYCS	PALB2	ATRIP	H2AFX	RAD23B	ERCC6	KAT5	TNFRSF10B	RBBP8	NEIL1	XPA	POLD4	APEX1	MDC1	TOPBP1	RAD50	REV1	SMC1A	TP53BP1	RFC5	RAD23A	ATM	TDG	GADD45A	APEX2	PCNA	CLSPN	HMGB1	TERT	FANCM	ERCC1	MGMT	POLH	XRCC4	DCLRE1C	MUS81	BRCA1	APTX	DDB1	RAD51D	CHEK2	RRM2B	PMS1	DNTT	CASP3	XRCC2	POLE	FANCL	NEIL2	CCND1	NHEJ1	FANCG	UBE2N	CCNB2	MPG	ERCC8	WRN	APAF1	MRE11A	ABL1	XRCC1	PTEN	MBD4	POLB	RAD1	RNF8	FANCD2	UNG	MUTYH	TP53	UBE2T	POLD1	PTTG1	TIMELESS	PRKDC	NPM1	FEN1	NEIL3	FANCE	SUMO1	HUS1	CASP9	CDK2	RNF168	BTG2	RAD51C	WDR48	GADD45G	MMS19	CDC25C	RFC3	RFC2	NTHL1	ERCC5	RAD54B	CDK1	LIG4	XRCC5	RPA2	XRCC3	FANCB	BARD1	ATR	MSH3	BAX	MLH3	RAD51B	LIG3	TREX1	BRCA2	FANCA	EXO1	PNKP	CDC6	TOP3A	POLD2	CASP8	XPC	CHEK1	ERCC3	XAB2	FAN1	PPM1D	CDC25A	FAS	XRCC6	APLF	RECQL4	POLL	ERCC2	MSH6	BLM	RFC4	SMARCAL1	ATRX	RFC1	NBN	BID	FANCC	RAD9A	RPA4	USP1	CEP164	RB1	MSH2	ERCC4	PMS2	RAD18	RAD52	SMUG1	DDB2	LIG1	EME1	UBR5	CDK7	FBXW7	POLD3	OGG1	MYC	DMC1	RPA1	RAD54L	PARP3	RAD21	PARP4	PARP1	FANCI	RPA3	RAD51	FANCF	MCM5	POLM	MLH1	PARP2	RAD17	MSH5	BRIP1																																																																																																																																																																																																																																																																																																																																																																																																																																																																																													
RESISTING CELL DEATH	STAT1	RIPK1	CYCS	MAP3K8	RHOA	CASP2	BCL3	NGF	LIMS2	FOXO3	DFFA	BTK	BNIP3L	MAPKAPK2	SOD2	TGFA	PLCG1	RASA1	TERT	BMP4	HSP90B1	FLT3	CD40LG	AIFM1	TNFRSF6B	FYN	BNIP3	MAP3K2	LTB	XIAP	ERBB3	CAMK2D	SFN	TNF	PRKACA	ITGB1	E2F1	HDAC1	CDC42	YWHAB	TSLP	BIRC2	PTEN	NSMAF	TNFSF10	SIX1	CD70	NPM1	AR	AKT1	SMAD2	CD44	ID1	GNG2	PLK3	EPO	SOCS3	IRS1	IL6R	BIRC5	SPHK1	ATR	CTNNA1	TNFRSF18	FGF4	STK11	BRCA2	TSC1	CASP8	HNF1A	BCL2L11	TNFRSF10C	CSF2RB	IL2RG	GZMB	CBL	IL12B	PRKAA1	IL7	RB1	TNFRSF10D	YWHAE	IGF1R	ESR2	BAG4	CCNG1	PIK3CB	DDB2	BFAR	IL6ST	TNFRSF21	MYC	ASAH1	IL7R	CX3CL1	BAD	ACVR1	MAPK7	RAB5A	JAK1	SMAD6	RPS6KB1	NTRK1	PIK3CA	YWHAG	IL2RB	SPTAN1	GAB1	CREB1	DDX3X	MAPK14	SYK	PTK2	BBC3	FOS	TNFRSF9	TLR4	MTOR	ARF4	TRAF1	IL5RA	ARHGDIA	RIPK2	PLD2	BAG1	SNCA	FOXO4	CDC73	PRKCE	KDR	COMP	HSP90AA1	VHL	BRCA1	RAF1	JUN	ATG5	KIT	EGFR	SMPD1	MAP3K7	VEGFB	APC	CASP3	NRG2	ERBB2	DIABLO	IL1B	FGF1	SOS1	GNB1	AGAP2	CCNB1	HGF	APAF1	CASP6	MLST8	MAP2K6	NOL3	SPHK2	CDK4	JAK2	SHC2	CD28	IL10	PAK2	LTA	ARAF	CDK2	ERBB4	SMAD3	E2F4	SMAD5	CDKN2A	SGK1	LMNA	IL5	BAX	GNAI3	SRC	NAIP	IFNG	HSPD1	IRS4	IKBKB	PAK1	MAPK12	RPS6KA5	PPARD	MSH2	THBS1	CLN3	KITLG	BIRC6	BRAF	FOXL2	TNFSF18	CHUK	IL3RA	TAB1	SIRT1	FGFR2	CCND2	NRG1	EGF	ESR1	NF1	RAC1	GRB2	RICTOR	EREG	IL2RA	CD27	PRKCZ	FLT4	TNFSF4	LCK	TNFRSF10B	NGFR	YWHAZ	PYCARD	PRF1	BECN1	PRLR	ATM	PLK1	PTPN11	BAG3	BCL6	PTK2B	MAP2K2	LEP	VTN	NODAL	TP53AIP1	TGFBR2	MAPKAPK3	BCL2L1	CD79B	ITCH	FOXO1	EP300	CAMK2A	CCND1	ELK1	MAP2K4	PDGFA	PIK3R1	BCL2	CDKN1A	MDM4	HSP90AB1	CFLAR	ABL1	TRAF7	E2F5	LRDD	TNFRSF10A	LTBR	NFKBIB	SHC3	GNAI1	NOTCH1	ITGA6	CASP9	ITGB4	WT1	BCL2L10	PLCG2	AKT2	PDGFRA	SORT1	NFKB1	MAP2K3	HSPB1	RPS6KA3	ERCC5	IL3	CRK	ADORA1	IL2	BCL10	CDK1	BNIP2	TCL1A	MAPK3	PDGFRB	CSF1R	BARD1	CASP10	CHEK1	TNFRSF1A	FAS	CAMK2B	IGF1	ACVR2A	TP63	VEGFC	IL12RB1	TRAF6	TRADD	GATA1	ITGAV	YWHAH	MDM2	MMP9	HRAS	PSEN1	TNFRSF1B	ANGPT2	PLK2	MAP4K4	NOD1	CRADD	STAT3	IL12RB2	CREBBP	HBEGF	PPP2R2A	CDKN1B	MCL1	CSF2RA	HIF1A	RAP1A	MAPKAP1	CAT	IL12A	LMNB1	CAMK2G	CSF2	GNAI2	DAPK1	TGFBR1	GSK3B	PIM1	NFKBIA	CASP7	NOS3	FGF2	PRKAA2	FADD	NRAS	IL4	VEGFA	CHEK2	MAP3K14	JAK3	IFNGR1	KRAS	IL6	NFE2L2	DDIT3	SMPD2	CD40	MAPK1	MAPK8	FIGF	MYOD1	PLD1	BCL2L2	MET	TP53	LMNB2	GRK5	TP73	HRK	PRKDC	ANGPT1	NRG3	CASP1	MAPK13	DAXX	PSMC5	BAK1	SHC1	BCL2A1	FKBP8	MAPK10	TNFRSF25	MAPK9	ITGB3	PAK4	AKT3	CASP5	PTPN13	EPAS1	RPS6KA1	PPP2R1A	CXCR2	ANGPT4	MAP2K1	HIP1	TNFRSF11B	CTSH	PTGS2	PPM1D	PPP2CA	MAP3K1	STAT5A	CTNNB1	TEK	BID	MAP2K7	FGF8	YWHAQ	GAB2	FASLG	BIRC3	CSF3R	TRAF2	CCNE1	RELA	FGFR3	MAPK11	PPT1	PRKCB	TNFSF8	NOTCH2	MAP3K5	MYB	MAP2K5	MLH1	RPS6																																																																																																																																																																																																																																								
EVADING GROWTH SUPPRESSORS	STAT1	RIPK1	MAP3K8	HDAC4	RHOA	WNT5B	INPP5D	NGF	FOXO3	LHCGR	CDH5	WNT10A	PPARG	LATS1	ABL2	ARRB1	PLCG1	RASA1	RRAS	FGF6	GNA15	PIK3CD	BMP4	DLG3	CSNK1D	CDKN2C	FGF16	PXN	PTCH1	SMAD1	ERBB3	PRKACB	SFN	TNF	PRKACA	S1PR1	RASAL2	HDAC1	YWHAB	PTEN	CBFA2T3	NSMAF	RALBP1	STK3	KLF4	CRKL	TFDP1	NPM1	AKT1	GNB2	IRS2	SMAD2	SPRY2	BMP7	RBL1	GNG10	GNG2	FGF17	CCND3	RASSF1	RPS6KB2	SOCS3	IRS1	WNT9A	PGF	ATR	FGF4	PRKCD	STK11	GNB5	EFNA1	TSHR	FGF3	RB1	EPHA2	YWHAE	IGF1R	MRAS	ARID2	RASGRP1	PIK3CB	WNT7A	WNT3A	EZH2	RASAL1	IL6ST	HTR7	INS-IGF2	GNAO1	MYC	RABEP1	MAPK7	ACVR1	ARF6	BAD	SHOC2	CDKN2B	ACVR2B	GNG13	SMAD6	RPS6KB1	NTRK1	PIK3CA	GNB3	RASSF6	YWHAG	GAB1	BRAP	WNT2	DDX3X	RASA2	RASAL3	MAPK14	PLA2G1B	ARAP2	MTOR	FGF11	FGF13	RIPK2	WNT8A	DLG4	FOXO4	CDC73	PRKCE	KDR	PDGFB	VHL	BRCA1	FZD2	RAF1	KIT	EGFR	FZD3	SMPD1	MAP3K7	FZD10	VEGFB	APC	DOK1	GATA3	CASP3	ARRB2	ERBB2	CALML5	FGF1	RGL1	PLCE1	SOS1	ACVR1B	GNB1	GPC3	HGF	NF2	MEN1	FGF22	MAP2K6	SPHK2	CDK4	JAK2	GNG11	PAK2	LATS2	GNA14	SOCS1	GNGT1	SMPD3	CDK2	RALA	ERBB4	MAPKAPK5	SMAD3	E2F4	SMAD5	CDKN2A	RAP1B	FZD7	GNAI3	SYNGAP1	SRC	WNT5A	HMOX1	WNT9B	IFNG	MAPK12	ADRB2	CDK6	RAC2	SAV1	THBS1	KITLG	ARHGAP26	SIRT1	RASGRF1	FGF7	NBL1	EGF	GNGT2	ESR1	NF1	RAC1	GRB2	WNT11	RRAS2	GNB4	PRKCZ	RALGDS	DNAJC25-GNG10	RASGRP2	NGFR	ETS1	PTPRT	YWHAZ	PTPN1	FZD5	MAPK6	NCK1	GNAZ	NDRG1	RGL2	ATM	CSNK1E	PTPN11	PLG	PBRM1	HNRNPK	MAP2K2	PDPN	AREG	NODAL	SKI	TGFBR2	MAPKAPK3	BCL2L1	HOXD10	FOXO1	EP300	MAX	BMPR2	PDGFA	MAP2K4	PIK3R1	BCL2	WNT16	CDKN1A	MDM4	KSR2	RBBP7	E2F5	SHC3	GNAI1	GNG5	NOTCH1	TGFB1	PLCG2	AGTR1	AKT2	PDGFRA	RBBP4	GRB10	NFKB1	MAP2K3	RASA4B	ZBTB17	CRK	MAPK3	PDGFRB	CSF1R	BARD1	GNG12	VAV1	RUNX3	TNFRSF1A	BMP5	GRIN2A	CAMK2B	IGF1	ACVR2A	VEGFC	WNT1	PLAU	TRAF6	TRADD	WNT4	SMAD4	AXIN1	LAT	PIK3R2	CDH1	YWHAH	BMP2	STMN1	KIF13B	AXIN2	HRAS	SMAD7	RASSF5	TIAM1	ANGPT2	WNT3	WNT7B	KSR1	MAP4K4	CYP1B1	CRADD	TGFB2	FGF12	STAT3	CREBBP	CDKN1B	FZD4	MCL1	CDK5	RAP1A	GNAI2	DAPK1	TGFBR1	GNG3	GSK3B	WNT2B	FGF2	NRAS	GJA1	VEGFA	CDH13	CEBPA	RASA4	ZFYVE16	ABCC1	BEX1	IFNGR1	KRAS	IL6	WNT10B	ROCK1	GNAS	SOX4	MAPK1	MAPK8	WNT8B	MAP3K10	CDK10	PDGFC	RASA3	MET	TP53	GNG4	TP73	STK4	FZD6	RIN1	PIK3CG	BAK1	SHC1	MAPK10	FGF9	MAPK9	ITGB3	PAK4	AKT3	RBM10	GNG8	EPAS1	PPP2R1A	RALB	ANGPT4	MAP2K1	CDC6	GNG7	BTRC	CSF1	PTGS2	FZD9	FGF14	TP53BP2	PPP2CA	FCGR2B	CTNNB1	TEK	DDIT4	PIK3R3	ABI1	MAP2K7	FGF8	YWHAQ	GAB2	PDGFD	FASLG	INSR	FGF21	FZD1	FGF18	FGF20	TRAF2	RELA	PRKCB	GNA11	CBLB	TGFB3	INHBA	NOTCH2	WNT6	FGF5	MAP2K5	LEFTY2	INS	GNAQ	FZD8																																																																																																																																																																																																																																																								
EVADING IMMUNE DESTRUCTION	STAT1	CXCR4	PTPN6	RHOA	STAT3	LCK	CD86	MAPK14	HCK	PTK2	HIF1A	PRF1	IL12A	CXCL12	ARRB1	GNAI2	PLCG1	PTPN11	CARD11	PIK3CD	PTK2B	BCL6	MAP2K2	NRAS	CD40LG	IL4	RAF1	CCL2	FYN	VAV2	CIITA	ARRB2	JAK3	IFNGR1	KRAS	IL6	SH2D1B	IL1B	CD3D	CD3E	CD40	MAPK1	LYN	PIK3R1	SOS1	GNB1	ADRBK1	FCGR3B	PTPRC	HCST	JAK2	CD28	PDCD1	FCGR3A	AKT1	CD8B	IRF7	PIK3CG	GNG2	AKT2	SHC1	HLA-A	IL2	AKT3	MAPK3	SH2D1A	FGR	B2M	PRKCD	SRC	PLCB3	CXCL10	MAP2K1	CD3G	ZAP70	IFNG	IKBKB	ITGB2	IL8	IL2RG	CBL	IL12B	PLCB2	CTNNB1	CD247	PIK3R3	TRAF6	CCL26	FES	CXCR1	PIK3R2	PIK3CB	CXCL9	VAV3	ITGAM	CD80	MAPK11	IL7R	PRKCB	HRAS	CBLB	RAC1	JAK1	TIAM1	GRB2	PIK3CA																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																					
SUSTAINED ANGIOGENESIS	CXCR4	CXCL13	FLT4	RHOA	TGFB2	GAB1	STAT3	LCK	FZD4	PDPK1	CDH5	HIF1A	MTOR	CXCL12	ITGA5	PLCG1	RRAS	ENG	TNFSF12	PTPN11	TGFBR1	TERT	PIK3CD	PTK2B	LEP	FGF2	NOS3	VTN	CCL24	SMO	KDR	PRKCG	RAF1	VEGFA	BRCA1	CCL2	TGFBR2	EGFR	VAV2	VEGFB	KRAS	IL6	ERBB2	PRKCA	ROCK1	TNF	IL1B	SDC4	PRKACA	CX3CR1	ITGB1	PDGFA	CD40	MAPK1	CXCL8	PIK3R1	FIGF	CSF3	HGF	VEGFD	IL10	MET	TP53	SDC2	TGFB1	AKT1	FLT1	CAV1	ARNT	ARHGEF1	PDGFRA	HSPB1	TWIST1	ITGB3	AKT3	MMP1	MAPK3	SPHK1	EPAS1	TIMP3	CXCR2	SRC	CXCL10	MAP2K1	WNT5A	EFNA1	IGF1	IL8	ROCK2	ACKR3	GATA2	VEGFC	CCR3	CTNNB1	TEK	FN1	EPHA2	IGF1R	THBS1	FES	ITGAV	CXCL9	CCL11	MYC	CXCR3	PRKCB	ACVRL1	HRAS	ESR1	TGFB3	PLAUR	RAC1	NF1	ANGPT2	GRB2	PIK3CA	IL1A																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																																										
SUSTAINING PROLIFERATIVE SIGNALING	STAT1	RIPK1	CXCR4	MAP3K8	RHOA	CDC25B	TBL1XR1	INPP5D	CHRM2	NGF	NFKB2	DGKB	ACER2	PPARG	ABL2	PPP1R12A	TGFA	ARRB1	GLI2	PLCG1	RASA1	CSNK1A1	RRAS	FGF6	IL13	PIK3CD	IL21	CACNA1I	RPTOR	BMP4	FLT3	GH2	CD40LG	CSNK1D	IL17D	PPP1R12B	FGF16	PXN	DGKI	MAP3K2	PTCH1	ERBB3	SMAD1	PRKACB	SFN	TNF	PRKACA	S1PR1	RASAL2	BAMBI	CSF3	PPP2R5E	NTF3	SERPINE1	MMP7	HDAC1	CDC42	MPL	YWHAB	TSLP	BIRC2	PTEN	NSMAF	CSNK1G2	FGF10	IL22	LPAR6	RALBP1	S1PR2	PKN1	STK3	SH2D2A	OSM	CRKL	NPM1	AR	AKT1	GNB2	IRS2	BMP7	TLR2	GNG10	GNG2	FGF17	SFRP5	HDAC2	CCND3	PLCD3	CRLF2	RASSF1	GNA12	RPS6KB2	EPO	SOCS3	PHLPP2	IRS1	PTPN5	IL6R	BIRC5	SLC44A4	SPHK1	PGF	MOS	CTNNA1	SUZ12	FGF4	PRKCD	STK11	PLCB3	ATF6B	CASP8	FGFR1	BCL2L11	GNB5	CSF2RB	IHH	ITGB2	DLG1	IL2RG	CBL	PLCD4	IL12B	SDCBP	ARHGEF7	PRKAA1	CSNK1G3	FGF3	NTRK2	IL7	FGF23	FN1	YWHAE	MRAS	PPP3CB	IGF1R	RASGRP1	PIK3CB	WNT7A	WNT3A	EZH2	RASAL1	DDX5	IL6ST	HTR7	INS-IGF2	GNAO1	GLI1	TJP1	LRP5	SUFU	MYC	ASAH1	IL7R	ACVR1	MAPK7	CXCR3	RAB5A	IL9	SHOC2	ACVR2B	JAK1	GNG13	RPS6KB1	NTRK1	PIK3CA	LPAR1	GNB3	RASSF6	SGMS1	YWHAG	IL2RB	GAB1	NCK2	WNT2	CREB1	CAV3	NTF4	RASA2	MED1	CBLC	FER	RHEB	RASAL3	MAPK14	SYK	PTK2	PRL	STAM2	STAT5B	PLA2G1B	FOS	ADORA3	TLR4	MTOR	FGF11	TRAF1	CXCL12	IL5RA	FGF13	PLCB1	RIPK2	PLD2	HCLS1	DLG4	PRKCE	PPP1R12C	KDR	PDGFB	HSP90AA1	GH1	BRCA1	RAF1	JUN	FZD2	KIT	EGFR	FZD3	VAV2	SMPD1	MAP3K7	FZD10	VEGFB	GATA3	CASP3	ARRB2	BDKRB2	NRG2	ERBB2	IL1R1	CALML5	SPDYA	IL1B	ID4	FGF1	RGL1	CHRM1	PLCE1	LYN	PIK3AP1	SOS1	ACVR1B	GNB1	CCNB1	IGF2	NF2	FGF22	MLST8	RAPGEF2	MAP2K6	SPHK2	RPS6KA6	NCOA2	CDK4	JAK2	TYK2	GNG11	IL10	ANK3	PAK2	ARAF	OSMR	DGKK	ADIPOQ	SOCS1	FLT1	GNGT1	SMPD3	YAP1	CDK2	ARHGEF1	ERBB4	RALA	MAPKAPK5	SMAD3	SMAD5	FOSL1	BDNF	IL5	CSH2	RAP1B	FZD7	ITGB5	GNAI3	DOK2	SYNGAP1	LPAR3	SRC	CSNK1A1L	IFNG	IKBKB	CXCL11	PAK1	IRS4	NTRK3	MAPK12	MAP3K13	PKN2	ACKR3	MS4A2	PPP2R5B	GATA2	CDK6	CNTF	RAC2	FGFR4	SAV1	THBS1	KITLG	RACGAP1	BRAF	CXCL9	ARHGAP26	RASGRF1	EZR	FGF7	FGFR2	LPAR4	TNXB	CCND2	EFNB2	OPRD1	PTK6	NBL1	STAM	NRG1	EGF	LIFR	ACVRL1	GNGT2	ESR1	GNA13	RAC1	CSNK2A1	NF1	GRB2	RRAS2	IL4R	EREG	IL2RA	GNB4	PRKCZ	FLT4	RALGDS	PTPN6	IL10RB	LPAR2	LCK	DNAJC25-GNG10	IL27	PTPRR	PTPRM	RASGRP2	NGFR	ACTB	IL20	YWHAZ	FZD5	ITPR2	NCK1	CSH1	ITPR1	GNAZ	NDRG1	RGL2	PRLR	ATM	CD79A	STAT2	WIF1	CSNK1E	PPP2R5A	PTPN11	LPAR5	PTK2B	MAP2K2	AREG	LEP	PTPN2	VTN	NODAL	PIP5K1A	NRG4	TGFBR2	MAPKAPK3	CD79B	FOXO1	EP300	CSNK1G1	MAX	STAT4	CCND1	ELK1	LIF	TNC	BMPR2	MAP2K4	PDGFA	CTF1	TEAD1	PIK3R1	BCL2	CALR	SHC4	CISH	ABL1	DGKD	KSR2	DGKZ	SHC3	GNAI1	GNG5	NOTCH1	TGFB1	MYD88	KAT2B	BMP6	PLCG2	MAPK8IP1	AKT2	HHIP	PDGFRA	THPO	NFKB1	MAP2K3	RASA4B	S1PR3	RPS6KA3	RET	IL3	CRK	ADORA1	DGKA	IL2	TCL1A	IL24	MAPK3	PDGFRB	CSF1R	BARD1	GNG12	ALK	VAV1	CHEK1	TNFRSF1A	BMP5	ACSL4	GRIN2A	FAS	CAMK2B	IGF1	ANK2	ROCK2	ACVR2A	GDF1	TP63	VEGFC	IL12RB1	WNT1	PLCB2	DGKE	PLAU	TRAF6	TRADD	LAT	ITGAV	FES	PIK3R2	YWHAH	IL11RA	SPP1	LAMC2	MDM2	CCL11	BMP2	STMN1	HPSE2	MAP3K6	ROS1	IQGAP1	HRAS	RASSF5	PLAUR	IL13RA1	CHN2	TIAM1	ANGPT2	LEF1	SH3BP5	CNTFR	KSR1	FGF19	PKN3	CXCL13	CRADD	TGFB2	FGF12	STAT3	IL12RB2	CREBBP	PPP2R2A	F2R	CDKN1B	FZD4	FLNB	MCL1	CSF2RA	PLCZ1	HIF1A	RAP1A	IL12A	CSF2	CSNK2B	GNAI2	SOCS5	PAG1	TGFBR1	IL19	NR4A1	GNG3	GSK3B	PIM1	FGF2	TCF7L2	PRKAA2	IL9R	ILK	ANK1	EPOR	SMO	NRAS	FADD	SMARCA2	DGKQ	IL4	PHLPP1	DGKH	VEGFA	ZFYVE16	RASA4	ELK4	JAK3	IL11	BEX1	IFNGR1	IL6	KRAS	GNAS	ROCK1	MAPK1	MAPK8	LRP6	SFRP2	FIGF	IL23R	S1PR4	WNT8B	GPC1	IL27RA	PLD1	CTNND1	PDGFC	RASA3	CREB3L2	MET	TP53	GNG4	PLCB4	STK4	FZD6	DGKG	RIN1	WWTR1	DNM2	PPP2R5C	DAXX	SHC1	THBS4	MAPK10	FGF9	MAPK9	ITGB3	PAK4	AKT3	GNG8	SHH	PLCD1	RPS6KA1	PPP2R1A	PRC1	EPAS1	RALB	ANGPT4	MED12	BTC	CACNA1D	MAP2K1	CXCL10	IL15	GSK3A	STAT6	GNG7	BTRC	CSF1	PTGS2	FZD9	NCOR1	FGF14	RPS6KA2	TP53BP2	PPP2CA	MAP3K1	STAT5A	CTNNB1	TEK	ABI1	MAP2K7	FGF8	YWHAQ	GAB2	PDGFD	FASLG	INSR	VLDLR	FGF21	FZD1	NANOGP8	S1PR5	SFRP1	FGF18	PPP2R5D	NLK	FGF20	CSF3R	TRAF2	SLC9A1	FGFR3	CCNE1	RELA	MAPK11	PRKCB	GNA11	IL23A	CBLB	TGFB3	KMT2D	INHBA	NOTCH2	FGF5	MAP2K5	LEFTY2	INS	HBEGF	GNAQ	FZD8	RPS6
TUMOR-PROMOTING INFLAMMATION	HLA-DRB3	PLCB2	CD8B	PRKCG	MYD88	RHOA	FCGR3A	TNFSF13B	PLAU	TLR2	GNG2	STAT3	FCGR2A	HLA-DRB1	NFKB1	NFKB2	KRAS	IL6	ROCK1	IL1R1	MAPK14	TNF	SYK	TNFAIP3	PRKACA	HLA-A	ADRBK2	MAP2K4	CD40	ITGAM	IL6ST	TLR4	PIK3R1	MYL2	SPN	GNB1	PRKCQ	ADRBK1	FCGR3B	MAPK11	GNAI2	ATM	GNAI3	PRKCB	PRKCD	PLCB1	PTPN11	CD22	CARD11	LY96	HRAS	PLCB3	CASP8	VASP	MAP2K1	JAK2	GNB5	IKBKB	ITGB2	ROCK2	PIK3CA	FCGR1A	PDCD1	CD276	GNAI1	FCGR2B